脑转移瘤；立体定向技术；放射治疗；X刀____

X线立体定向放射治疗脑转移瘤临床分析

http://www.100md.com 《实用医技杂志》 2007年第6期

脑转移瘤；立体定向技术；放射治疗；X刀,,],脑转移瘤；立体定向技术；放射治疗；X刀,1材料与方法,2结果,3讨论,参考文献：

     [摘要] 目的：探讨X线立体定向放射治疗脑转移瘤的临床价值。方法：采用X线立体定向技术，单次、大剂量照射脑转移瘤，设4个～9个非共面照射野，80%等中心剂量线覆盖PTV。多发转移灶，根据肿瘤所在位置、大小及局部周边水肿情况和全身状况配合全脑照射。结果：424例患者均顺利完成治疗全程，成功率100%。加速器等中心精确度(0.5±0.2) mm，无严重副反应。6个月、12个月、24个月生存率分别为87%、75%和15%，中位生存10.7个月。结论：X线立体定向放射治疗技术治疗脑转移瘤精度高、近期改善局部症状快、损伤小且安全，尤其对单发的小病灶(≤3 cm)具有较高的临床价值。

    [关键词] 脑转移瘤；立体定向技术；放射治疗；X刀

    Clinical Analysis of Radiotherapy in Treating Brain Metastases through Xray Tridimensional Stereotactic

    LIU Gang,YUAN Jin,CHEN Su

    (Fuzhou Hospital of Nanjing melitary area,Fuzhou,Fujian 350025,China)

    Abstract:Objective To evaluate the effect of Xray stereotactic radiotherapy in the treatment of brain metastases.Methods Brain metastases of all patients were radiated with highdose Xrays stereotactic radiosurgery(SRS)only one fraction,which including 4 to 9 noncoplane fields and whose PTV were enveloped 80% isocenter dose.The patients with multiple brain metastases were wholebrain radiated after SRS.Results The isocenter accuracy of accelerator was 0.5 mm±0.2 mm.All 424 patients accomplished their treatment and had not severe sideeffect.Their 6 monthssurvival ......

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