纳络酮加丹参注射液治疗重度新生儿HIE的 临床研究
缺氧缺血性脑病;,新生儿;,纳络酮;,丹参,,缺氧缺血性脑病;,新生儿;,纳络酮;,丹参,纳络酮加丹参注射液治疗重度新生儿HIE的临床研究,1对象与方法,2结果,3讨论,参考文献
【摘要】 目的 观察使用纳络酮加丹参注射液治疗重度新生儿缺氧缺血性脑病(HIE)的疗效。方法 35例重度HIE患儿随机分为两组，观察组20例，对照组15例。除进行相同的常规治疗外，观察组给予纳络酮静滴，连用5 d，丹参注射液加10%GS静滴，疗程28 d。观察患儿临床症状的变化，并随访12个月，观察神经系统后遗症的发生率。结果 观察组患儿临床症状明显改善，神经系统后遗症发生率较低。结论 纳络酮加丹参注射液治疗重度新生儿HIE疗效显著。【关键词】 缺氧缺血性脑病; 新生儿; 纳络酮; 丹参
A Clinical Study on Treating Hypoxic Ischemic Encephalopathy of Newborn with Naloxone Adding Radix Salviae Miltiorrhizae Injection ZHENG Zhiyu，YANG Ming，LIAO Fuqiang，et al.Department of Paediatrics, the People's Hospital of Fogang County, Guangdong 511600,China
【Abstract】 Objective Observing the effect of Naloxone adding Radix salviae miltiorrhizae in treating hypoxic ischemic encephalopathy of newborn. Methods 35 cases were randomly divided into 2 groups,which include observed group (20 cases) and control group (15 cases). Both were given general treatment, and the observed group was treated with Naloxone adding Radix salviae miltiorrhizae. Attention was paid to the changes on clinical symptoms and signs of the newborn patients. Based on a 12month followup visit of all patients, observation was focused on the occurrence rate of sequelae of nerve system. Results The observed group had obvious improvement in clinical symptoms and a low occurrence rate of sequelae of nerve system. The results showed significant difference from the control group. Conclusion Treating hypoxic ischemic encephalopathy of newborn with Naloxone adding Radix salviae miltiorrhizae is effective. ......
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