紫癜_过敏性；_过敏原_；诊断；_治疗；儿童____

食物过敏原试验对过敏性紫癜病因分析和治疗意义

http://www.100md.com 《齐鲁医学杂志》 2007年第2期

紫癜,过敏性；,过敏原,；诊断；,治疗；儿童,,],紫癜,过敏性；过敏原；诊断；治疗；儿童,1对象与方法,2结果,3讨论,[参考文献]

     [摘要] 目的探讨体外食物过敏原试验对确定儿童过敏性紫癜(HSP)病因和指导饮食控制辅佐治疗HSP的价值。方法选择60例HSP病儿(HSPⅠ组)为研究对象，以30例正常儿童为对照组，采用酶免疫分析法进行体外食物过敏原检测；以45例未行食物过敏原试验的HSP病儿(HSPⅡ组)为对照组，比较不同饮食控制疗法的近期疗效。结果 HSPⅠ组血清总IgE阳性率、过敏原检测阳性率与正常对照组比较差异有极显著意义(χ2=8.038、7.500，P<0.01)；HSPⅠ组中同时对两类或两类以上食物过敏原检测阳性率高于正常对照组(χ2=4.821，P<0.05)；HSPⅠ组海产品类和蔬菜类检测阳性率明显高于对照组(χ2=4.821、4.226，P<0.05)。HSPⅠ组病儿根据体外食物过敏原试验结果进行饮食控制，与常规行忌食动物蛋白和海产品类饮食的HSPⅡ组比较，随访3个月期间紫癜反复或复发率差异显著(χ2=4.507，P<0.05)。结论过敏原检测有助于确定HSP的病因；海产品和蔬菜类食物过敏为本地区儿童HSP的重要诱发因素；通过针对性饮食控制可有效控制或减少HSP的反复或复发，对HSP的防治有重要临床意义。

    [关键词] 紫癜,过敏性；过敏原；诊断；治疗；儿童

    EVALUATION OF THE FOOD ALLERGEN TEST IN ETIOLOGICAL ANALYSIS AND TREATMENT GUIDANCE OF HENOCHSCHONLEIN PURPURA IN CHILDRENWANG YEJUN, ZHANG QIUYE, XU JING (Deparement of Internal Medicine, Qingdao Medical Care Center for Women and Children, Qingdao 266011, China)

    [ABSTRACT]ObjectiveTo evaluate the food allergen test in the etiology analysis of HenochSchonlein purpura (HSP) and alimentary control in the treatment of HSP in children. MethodsSixty children with HSP (HSP Ⅰ group) and 30 healthy children as normal control were studied via enzyme immunoassay to test food allergen. Another 45 children with HSP not undergoing the test were included as experimental control (HSPⅡgroup). ResultsThe positive rate of the total serum IgE and allergen in the HSP Ⅰ group was significantly higher than that of the normal control group (χ2=8.038,7.500;P<0.01). The percentage of children in the HSP Ⅰ group, who were positive to two, or more than two food allergens, were higher than that of the normal control group (χ2=4.821 ......

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