Diagnosis and treatment of advanced prostatic cancer (report of 84 cases)

    Li Junsheng, Tang Laikun, Yang Yincai, Li Li, Pan Liang, Sha Jian, Tian Feng, Cheng Jie, Jiang Yu

    (Department of Urology, Xuhui District Central Hospital, Shanghai, 200031; Department of Urology, Jiren Hospital, Shanghai 200001, China)

    ABSTRACT: Objective To improve the diagnosis and treatment of advanced prostatic cancer. Methods Eightyª²four cases of lateª²stage prostatic cancer were reviewed in this study. All the patients underwent bilateral orchiectomy and endocrinal therapy (flutamide); 22 cases with severe ureteric obstruction were treated by transurethral resection of prostate; 3 cases underwent radical protatetomy; 3 cases were treated by interventional chemotherapy. Results 78 cases were followed up for 3-24 months. 46 cases were followed up for 5 years. The subjective symptoms and objective signs were improved; the obstruction of bladder outlet and bone pain were relieved to different extent; PSA decreased and the life quality was improved apparently. Conclusion Bilateral orchiectomy and endocrinal therapy were effective to inhibit the growth of cancer. TURP can relieve bladder outlet obstruction. ......