240对自然流产夫妇染色体异常分析
自然流产;外周血;染色体;异常核型,,自然流产;外周血;染色体;异常核型,1对象与方法,2结果,3讨论,参考文献
摘要 目的:探讨自然流产夫妇与染色体异常的关系。方法:采用外周血淋巴细胞染色体培养技术,G显带,显微镜下核型分析,计数20个核型,分析3个核型。结果:240对流产夫妇中发现染色体异常病例31例,检出率为(12.9%)。结论:染色体异常是导致流产的重要原因之一,应对这类患者进行常规细胞遗传学检查。关键词 自然流产;外周血;染色体;异常核型
Abnormal Chromosome Analysis of 240 cases with Self-generating Abortion
Yang Hongmei
Reproductive Medicine Center of Heping Hospital of Changzhi Medical College
Abstract Objective:To investigate the relationship between self-generating abortion couples and abnormal chromosome which have been inspected in the 240 couples.Methods: Peripherral lymphooytes were detected by cytogeneties method,G-banding,Assayed karyotypes under microscope,take count of 20 karyotypes,analysed 3 of them.Results:31 Abnormal chromosome was found in 240 couples,accounting to 12.9%.Conclusion: The abnormality of chromosome is one of reasons of self-generating abortion, thus, usual chromosome examination is necessary for this kind of valetudinarians.
Key words Self-generating abortion; Peripheral blood; Chromosome; Abnormal karyotypes
人类可识别的自然流产的发生率约为15%[1] ......
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