健脾益肺化淤方对小鼠Lewis 肺癌作用的研究
健脾益肺化淤方；,小鼠；,抑瘤作用；,协同增效,,健脾益肺化淤方；,小鼠；,抑瘤作用；,协同增效,健脾益肺化淤方对小鼠Lewis肺癌作用的研究,1材料与方法,2结果,3讨论,参考文献：
摘要：目的探讨健脾益肺化淤方对肺癌的抑制和对化疗的协同增效作用。方法选择小鼠移植性Lewis 肺癌为模型， 观察健脾益肺化淤方以及与化疗药物顺铂(DDP) 联合应用时的抑瘤率。结果健脾益肺化淤方对小鼠移植性Lewis 肺癌有显著的抑制作用(P<0. 05) , 并能显著增强DDP 对小鼠Lewis肺癌的抑瘤作用(P<0. 01) 。结论健脾益肺化淤方对小鼠Lewis肺癌有抑制和对化疗药物有协同增效作用。关键词：健脾益肺化淤方； 小鼠； 抑瘤作用； 协同增效
Effect of Jianpi Yifei Huayu Formula on Lewis Lung Cancer in Mice
MENG Hua， CAO Yong，XIA Qinghua
(Department of Traditional Chinese Medicine,Medical College of Jinan University，Guangzhou510632, China)
Abstract：ObjectiveTo explore the effect of Jianpi Yifei Huayu formula on tumor and its synergy with chemotherapy in lung cancer.MethodsLewis lung cancer model of transplanted mice were used, the inhibitory rates of Jianpi Yifei Huayu formula and its combination with cisplatin (DDP) on tumor were observed.ResultsJianpi Yifei Huayu formula significantly inhibited Lewis lung cancr in transplanted mice (P<0. 05) ，and enhanced the effect of DDP (P<0. 01) . ConclusionJianpi Yifei Huayu formula has inhibition effect and can increase synergy with chemotherapy on lung cancer of transplanted animals. ......
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