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老年冠心病患者血清铁、铁蛋白及血脂水平的研究
http://www.100md.com 《中华实用医药杂志》 2007年第1期
血清铁;血清铁蛋白;血脂;冠心病,,血清铁;血清铁蛋白;血脂;冠心病,1资料与方法,2结果,3讨论,【参考文献】
     【摘要】 目的 探讨老年人血清铁、血清铁蛋白、血脂水平与老年冠心病(CHD)的关系。方法 对109例老年冠心病患者及74例老年对照组进行了血清铁、血清铁蛋白测定,对两组的血脂、脂蛋白(a)也进行了测定。结果 老年冠心病患者血清铁、血清铁蛋白(SF)水平显著高于对照组;老年冠心病患者血清胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)及脂蛋白(a)[ Lp(a)] 含量显著高于对照组,而高密度脂蛋白胆固醇(HDL-C)、载脂蛋白AⅠ(apoAⅠ)含量却显著低于对照组。结论 体内铁储存增加与老年CHD的发生和发展密切相关。对老年CHD来说,有高血清Fe、SF和高血清LDL-C和Lp(a)的人有明显的心脏病高发危险,故在临床上测定血脂的同时测定血清Fe、SF对老年CHD的诊断和预测具有一定的意义。

    【关键词】 血清铁;血清铁蛋白;血脂;冠心病

    The levels of serum iron, serum ferritin, blood lipid and CHD in aged people

    YE Ji-cheng, ZHOU Xiao-gang. The Teaching and Research Room of the Biochemistry and Molecular Biology, Internal Mongolia Medical College, Huhehaote 010050, China

    【Abstract】 Objective To study the level of serum iron, serum ferritin and blood lipid with the aged people bearing coronary heart disease(CHD). Methods The concentration of serum iron and serum ferritin in 109 cases of aged patients with CHD and 74 cases of normal controls were determined. The levels of blood lipids and lipoprotein (a) were also measured in the two groups. Results The concentration of SF in aged patients with CHD were markedly higher; The levels of TC, LDL-C, and Lp(a) are significantly higher than that of control, while the levels of HDL-C, apoAⅠ are significantly lower in aged patients with CHD than those of the controls. Conclusions High stored iron levels are associated with the developing of coronary heart disease. The high levels of Fe, SF, LDL-C and Lp(a) can increase the risk of heart disease of old people. Measuring the levels of blood lipid, as well as the concentration of Fe, SF, can be help for the diagnosis and forecast for the aged people with CHD. ......

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