【摘要】 目的 运用药物经济学原理，比较3种抗生素治疗中重度下呼吸道感染的疗效和费用。方法 回顾性调查我院2004年8月～2005年7月应用3种抗生素治疗中重度下呼吸道感染的96例临床病历，分析了其药物利用及成本消耗情况。结果 疗效-成本分析表明，哌拉西林 /他唑巴坦具有较好的疗效成本比。结论 3组的DUI值均<1，表明我院该类用药基本是合理的。

    【关键词】 亚胺培南/西司他丁； 哌拉西林/他唑巴坦；头孢唑肟；成本-效果分析；下呼吸道感染

    Analysis by pharmaceutical-economic principle to comparing the three antibiotics in the treatment of lower respiratory tract infection

    LIU Gang.

    Tianjin Economic Technological Development Area Hospital，Tianjin Tanggu 300457，China

    【Abstract】 Objective By using pharmaceutical-economic principle to comparing the curative effect and cost of three antibiotics in the treatment of lower respiratory tract infection.Methods Retrospective sampling was administered to get 96 severe lower respiratory tract infection cases during the period of Aug 2004 to July 2005 and the administration of medicine and the cost-effectiveness are analyzed.Results Cost-effectiveness analysis shows that piperacillin/tazobactam have better ratio of effectiveness to cost.Conclusion The DUI values of all three groups are lower than 1 ......