英文摘要
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中国现代医学杂志990446CHANGES OF NK ACTIVITY AND T LYMPHOCYTE
SUBSETS IN PATIENTSWITH THE PRIMARY GALLBLADDER CARCINOMA DUE TO OPERATION
Shi Jingsen,Liu Gang,Yu Yueli，et al.
The Department of Hepato biliary Surgery,First Affiliated Hospital of
The Xi'an Medical University，Xi'an，Shanxi 710061,P.R.China
Objective:To compare the functions of natural immunity and acquired immunity in patients with primary gallbladder carcinoma (PGC) before operation after operation.Methods:Fifteen patients with PGC and twenty-five normal persons were investigated by means of minute with those cell toxin experiment-LDH enzyme release assay and alkaline phosphoric acid enzyme-anti alkaline phosphoric acid enzymea (PAP),in order to detect changes of NK activity and T lymphocyte subsets postoperation alignmently.Results:Both the NK activity and CD3+ and CD4+ cell of T lymphocyte in patients with PGC are lower than those of normal persons significantly(P<0.001)，While the CD8+ cell is increased and the ratio of CD4+/CD8+ is decreased,Several cell immunity function indexes were decreased furtherly and a immunity restrain period of short duration has emerged postoperatively Afterwards,each immunity index was resumed gradually,The time of restrain period was cbsely related to the prognosis of the patients with PGC.Conclusion: The radical operation of PGC can eliminate such tumor immunity restrain and enhance the NK activity and the percentage of CD3+ and CD4+,The result showed that comparing NK activity and T lymphocyte subsets before operation with those after operation in patients with PGC regularly would here contribute to evaluate prognosis correctly. ......
您现在查看是摘要页，全文长 9792 字符。
单位：
关键词：
中国现代医学杂志990446CHANGES OF NK ACTIVITY AND T LYMPHOCYTE
SUBSETS IN PATIENTSWITH THE PRIMARY GALLBLADDER CARCINOMA DUE TO OPERATION
Shi Jingsen,Liu Gang,Yu Yueli，et al.
The Department of Hepato biliary Surgery,First Affiliated Hospital of
The Xi'an Medical University，Xi'an，Shanxi 710061,P.R.China
Objective:To compare the functions of natural immunity and acquired immunity in patients with primary gallbladder carcinoma (PGC) before operation after operation.Methods:Fifteen patients with PGC and twenty-five normal persons were investigated by means of minute with those cell toxin experiment-LDH enzyme release assay and alkaline phosphoric acid enzyme-anti alkaline phosphoric acid enzymea (PAP),in order to detect changes of NK activity and T lymphocyte subsets postoperation alignmently.Results:Both the NK activity and CD3+ and CD4+ cell of T lymphocyte in patients with PGC are lower than those of normal persons significantly(P<0.001)，While the CD8+ cell is increased and the ratio of CD4+/CD8+ is decreased,Several cell immunity function indexes were decreased furtherly and a immunity restrain period of short duration has emerged postoperatively Afterwards,each immunity index was resumed gradually,The time of restrain period was cbsely related to the prognosis of the patients with PGC.Conclusion: The radical operation of PGC can eliminate such tumor immunity restrain and enhance the NK activity and the percentage of CD3+ and CD4+,The result showed that comparing NK activity and T lymphocyte subsets before operation with those after operation in patients with PGC regularly would here contribute to evaluate prognosis correctly. ......
您现在查看是摘要页，全文长 9792 字符。