静磁场作用下大鼠牙槽骨中前列腺素E2变化的研究
作者：常新 秦科 吕永利
单位：常新 秦科(中国医科大学口腔医学院正畸科)；吕永利(基础医学院解剖学教研室 沈阳110002)
关键词：前列腺素E2；静磁场；非磁场；牙槽骨
解剖科学进展000315 摘 要：目的：通过对大鼠在静磁场和非磁场作用下其牙槽骨的内源性前列腺素E2随时间变化的对比研究，了解在静磁场作用下，大鼠牙槽骨中前列腺素E2含量的时间变化性。方法：放射免疫法检测20只加静磁场、20只加非磁场和4只空白对照的大鼠牙槽骨中前列腺素E2的含量，探讨静磁场对大鼠牙槽骨的内源性前列腺素E2的变化的影响。结果：未受力时，大鼠的牙槽骨内即存在一定数量的前列腺素E2。在静磁场作用下，牙槽骨的内源性前列腺素E2在1 h内即开始升高，在6 h时达高峰，随即开始下降，但速度缓慢，24 h时仍高于正常。加非磁场组前列腺素E2的变化趋势同加磁场组，但前列腺素E2开始反应慢，峰值却高于加磁场组。且12，24 h时的前列腺素E2水平亦高于加静磁场组。结论，牙槽骨的内源性前列腺素E2的变化与静磁场的生物学效应有关。
, 百拇医药
Changes of Prostaglandin E2 Level in the Alveolar of Rats in Static Magnet Field
Chang Xin ,Qin Ke ,Lu Yong Li
(Department of Orthodontics, Stomatology Hospital, China Medical University, Shen Yang, 110002)
Abstract：This experiment studied the changes of prostaglandinE2 lever in the alveolar of rats in static and non-magnetic fields in order to understand the changes of prostaglandin E2 in the alveolar of rats with the time in static magnetic field. Methods :Radioimmunoassay was used to examine the level of prostaglandin E2 in the alveolar of 20 rats in static magnetic field, 20 rats in non-magnetic field, and 4 control rats. Results:There is prostaglandin E2 in the alveolar of rats under no influences. In static magnetic field the prostaglandin E2 level in the alveolar began to rise within an hour, and arrived at its peak at 6 hours, then began to go down slowly, but still high at 24 hours as compared with the standard. As for the non-magnetic field group, the changing trend is same with the static magnetic field group although the starting speed is slow, the peak and the level of the 12 hours, 24 hours are also higher than the static magnetic field group. Conclusion:We think that this phenomenon is concerned with the biological effects of static magnetic field.
, 百拇医药
Keywords：prostaglandin E2; static magnetic field; non-magnetic field; alveolar
参考文献：
[1]Davidovitch. Z, Nicolay OF, Ngan PW. Neurotransmitters, cytokines, and the control of alveolar bone remodeling in orthodontics. Dent Clin North Am, 1988, 32(3): 411-35
[2]Yamasaki K, Miura F, Suda T. Prostaglandin as a mediator of bone resorption induced by experimental tooth movement in rata. J Dent Res, 1980, 59(10): 1635-42
[3]于晓惠，陶宏惠，付民魁.前列腺素对鼠牙槽骨破骨活动的作用.现代口腔医学杂志，1990; (4)：202-204
[4]张丁，付民魁，任玉香.鼠牙移动过程中齿槽骨前列腺素含量变化的研究.中华口腔医学杂志，1992，27(5)，290-292
[5]赵桂芝，陈华，林珠.恒磁场对人牙周膜成纤维细胞DNA代谢的影响.中华口腔医学杂志，1994，29(2)，75-78, 百拇医药
单位：常新 秦科(中国医科大学口腔医学院正畸科)；吕永利(基础医学院解剖学教研室 沈阳110002)
关键词：前列腺素E2；静磁场；非磁场；牙槽骨
解剖科学进展000315 摘 要：目的：通过对大鼠在静磁场和非磁场作用下其牙槽骨的内源性前列腺素E2随时间变化的对比研究，了解在静磁场作用下，大鼠牙槽骨中前列腺素E2含量的时间变化性。方法：放射免疫法检测20只加静磁场、20只加非磁场和4只空白对照的大鼠牙槽骨中前列腺素E2的含量，探讨静磁场对大鼠牙槽骨的内源性前列腺素E2的变化的影响。结果：未受力时，大鼠的牙槽骨内即存在一定数量的前列腺素E2。在静磁场作用下，牙槽骨的内源性前列腺素E2在1 h内即开始升高，在6 h时达高峰，随即开始下降，但速度缓慢，24 h时仍高于正常。加非磁场组前列腺素E2的变化趋势同加磁场组，但前列腺素E2开始反应慢，峰值却高于加磁场组。且12，24 h时的前列腺素E2水平亦高于加静磁场组。结论，牙槽骨的内源性前列腺素E2的变化与静磁场的生物学效应有关。
, 百拇医药
Changes of Prostaglandin E2 Level in the Alveolar of Rats in Static Magnet Field
Chang Xin ,Qin Ke ,Lu Yong Li
(Department of Orthodontics, Stomatology Hospital, China Medical University, Shen Yang, 110002)
Abstract：This experiment studied the changes of prostaglandinE2 lever in the alveolar of rats in static and non-magnetic fields in order to understand the changes of prostaglandin E2 in the alveolar of rats with the time in static magnetic field. Methods :Radioimmunoassay was used to examine the level of prostaglandin E2 in the alveolar of 20 rats in static magnetic field, 20 rats in non-magnetic field, and 4 control rats. Results:There is prostaglandin E2 in the alveolar of rats under no influences. In static magnetic field the prostaglandin E2 level in the alveolar began to rise within an hour, and arrived at its peak at 6 hours, then began to go down slowly, but still high at 24 hours as compared with the standard. As for the non-magnetic field group, the changing trend is same with the static magnetic field group although the starting speed is slow, the peak and the level of the 12 hours, 24 hours are also higher than the static magnetic field group. Conclusion:We think that this phenomenon is concerned with the biological effects of static magnetic field.
, 百拇医药
Keywords：prostaglandin E2; static magnetic field; non-magnetic field; alveolar
参考文献：
[1]Davidovitch. Z, Nicolay OF, Ngan PW. Neurotransmitters, cytokines, and the control of alveolar bone remodeling in orthodontics. Dent Clin North Am, 1988, 32(3): 411-35
[2]Yamasaki K, Miura F, Suda T. Prostaglandin as a mediator of bone resorption induced by experimental tooth movement in rata. J Dent Res, 1980, 59(10): 1635-42
[3]于晓惠，陶宏惠，付民魁.前列腺素对鼠牙槽骨破骨活动的作用.现代口腔医学杂志，1990; (4)：202-204
[4]张丁，付民魁，任玉香.鼠牙移动过程中齿槽骨前列腺素含量变化的研究.中华口腔医学杂志，1992，27(5)，290-292
[5]赵桂芝，陈华，林珠.恒磁场对人牙周膜成纤维细胞DNA代谢的影响.中华口腔医学杂志，1994，29(2)，75-78, 百拇医药