眼冲击伤致伤机理初探
作者：黄秋闽 杨志焕 王正国 冷华光 李晓炎
单位：黄秋闽(北京军区总医院眼科，北京100700)；杨志焕 王正国 冷华光 李晓炎 (第三军医大学附属大坪医院野战外科研究所，重庆400042)
关键词：跟冲击伤；致伤机理；生物力学
创伤外科杂志000313摘 要：目的初步探讨眼冲击伤的致伤机理。方法采用BST-Ⅲ型生物激波管，建立U压力峰值(429±38.8)kPa和(834±6.4)kPa的轻、重两组伤型的眼冲击伤模型。在对不同强度的冲击波对眼组织的早期损伤的系列实验研究的同时，从临床损伤特点和生物力学角度讨论了眼冲击伤的致伤机理。结果冲击波在眼部形成的眼内应力反射效应、应力剥落效应、压缩波与拉伸波的复合效应，可造成眼冲击伤特有的一些损伤特点。结论眼冲击伤与眼钝挫伤的致伤机制有所不同。
分类号：R642 文献标识码：A
, http://www.100md.com
文章编号：1009-4237(2000)03-0165-03
A preliminary exploration of pathogenesis of ocular blast injury
HUANG Qiu-min,YANG Zhi-huan,WANG Zheng-guo
(Department of Ophthalmolgy, Ceneral Hospital of Beijing Unit of PLA. Beijing 100700)
Abstract：Objective The manifestations of ocular posterior segment injuries by blast wave at the early stage and the mechanism of ocular blast injury were explored. Methods In this study, the BST-Ⅲ bioshock tube was used to inflict ocular blast injury in rabbits. The peak pressure values for inflicting the mild and severe injuries were(429±38.8)kPa(8.9 ±1. 8)ms and (834±6.4 )kPa(6.6±1.7)ms, respectively. We used detection of CBF, ERG, FFA, and pathohistolngy. The early changes of tissue damage to ocular posterior segment(retina, choroi and optic nerve)were dynamically observed. Results At the early stage of ocular blast injury, every target of detections has marked difference. Conclusion The direct damage to retina, choroid and optic nerve, the reduction of CBF and retinal metabolic disorder caused by blast wave were the key factors of visual disfunction. Based on the clinical characteristics and from the view of biomechanics, it is suggested that the pathogenesis of ocular blast injury was different from that of ocular blunt injury.
, 百拇医药
Keywords：ocular blast injury; pathogenesis; biomechanics
参考文献：
[1]孙立英，王正国，李晓炎，等.微型生物激波管的研制及其在家兔眼冲击伤实验中的应用[J].第三军医大学学报，1991，13(5)：469.
[2]王正国，冲击伤[M].北京：人民军医出版社，1983.16.
[3]郑宝仁.眼外伤[M].福州：福州军区总压院.1977.252.
[4]袁良礼，王正国，杨志焕，等.眼冲击伤的实验研究[J].中华创伤杂志，1992，(8)：114.
[5]高绍辉.兔眼冲击伤眼前节伤情及血-房屏障变化[D].第三军医大学硕士研究生论文，1992.8-12.
[6]Wolter JR.Coup-contrecoup mechanism of ocular injuries[J].Am J Ophthalmol，1963，56：785-796.
[7]Courville CB.Coup-contrecoup mechanism of cranilcerebral injuries[J].Arch Surg，1942；45：19-22.
收稿日期：1999-10-12
修稿日期：2000-05-10, 百拇医药
单位：黄秋闽(北京军区总医院眼科，北京100700)；杨志焕 王正国 冷华光 李晓炎 (第三军医大学附属大坪医院野战外科研究所，重庆400042)
关键词：跟冲击伤；致伤机理；生物力学
创伤外科杂志000313摘 要：目的初步探讨眼冲击伤的致伤机理。方法采用BST-Ⅲ型生物激波管，建立U压力峰值(429±38.8)kPa和(834±6.4)kPa的轻、重两组伤型的眼冲击伤模型。在对不同强度的冲击波对眼组织的早期损伤的系列实验研究的同时，从临床损伤特点和生物力学角度讨论了眼冲击伤的致伤机理。结果冲击波在眼部形成的眼内应力反射效应、应力剥落效应、压缩波与拉伸波的复合效应，可造成眼冲击伤特有的一些损伤特点。结论眼冲击伤与眼钝挫伤的致伤机制有所不同。
分类号：R642 文献标识码：A
, http://www.100md.com
文章编号：1009-4237(2000)03-0165-03
A preliminary exploration of pathogenesis of ocular blast injury
HUANG Qiu-min,YANG Zhi-huan,WANG Zheng-guo
(Department of Ophthalmolgy, Ceneral Hospital of Beijing Unit of PLA. Beijing 100700)
Abstract：Objective The manifestations of ocular posterior segment injuries by blast wave at the early stage and the mechanism of ocular blast injury were explored. Methods In this study, the BST-Ⅲ bioshock tube was used to inflict ocular blast injury in rabbits. The peak pressure values for inflicting the mild and severe injuries were(429±38.8)kPa(8.9 ±1. 8)ms and (834±6.4 )kPa(6.6±1.7)ms, respectively. We used detection of CBF, ERG, FFA, and pathohistolngy. The early changes of tissue damage to ocular posterior segment(retina, choroi and optic nerve)were dynamically observed. Results At the early stage of ocular blast injury, every target of detections has marked difference. Conclusion The direct damage to retina, choroid and optic nerve, the reduction of CBF and retinal metabolic disorder caused by blast wave were the key factors of visual disfunction. Based on the clinical characteristics and from the view of biomechanics, it is suggested that the pathogenesis of ocular blast injury was different from that of ocular blunt injury.
, 百拇医药
Keywords：ocular blast injury; pathogenesis; biomechanics
参考文献：
[1]孙立英，王正国，李晓炎，等.微型生物激波管的研制及其在家兔眼冲击伤实验中的应用[J].第三军医大学学报，1991，13(5)：469.
[2]王正国，冲击伤[M].北京：人民军医出版社，1983.16.
[3]郑宝仁.眼外伤[M].福州：福州军区总压院.1977.252.
[4]袁良礼，王正国，杨志焕，等.眼冲击伤的实验研究[J].中华创伤杂志，1992，(8)：114.
[5]高绍辉.兔眼冲击伤眼前节伤情及血-房屏障变化[D].第三军医大学硕士研究生论文，1992.8-12.
[6]Wolter JR.Coup-contrecoup mechanism of ocular injuries[J].Am J Ophthalmol，1963，56：785-796.
[7]Courville CB.Coup-contrecoup mechanism of cranilcerebral injuries[J].Arch Surg，1942；45：19-22.
收稿日期：1999-10-12
修稿日期：2000-05-10, 百拇医药