作者单位：250031 济南，山东济南军区总医院消化内科

    干细胞移植治疗肝硬化的研究进展

    吴颖孙自勤江学良刘晓峰王要军

    【摘要】肝硬化是临床上常见的一种消化系统慢性疾病，是多种肝病患者疾病进展的终末阶段。失代偿期肝硬化患者会出现多种严重并发症，甚至危及生命。干细胞是组织中具有多潜能性、自我更新的细胞。近年来，随着干细胞技术的成熟和发展，干细胞移植治疗肝硬化患者取得了良好的疗效，具有广阔的发展前景。该文对干细胞移植治疗肝硬化的研究现状和进展进行阐述。

    【关键词】肝硬化；干细胞；移植

    DOI:10.3969/g.issn.0253-9802.2015.06.002

    通讯作者，吴颖，E-mail:leaf19832200@sina.com

    收稿日期：(2015-02-06)

    Research progress in stem cell transplantation in the treatment of liver cirrhosisWuYing,SunZiqin,JiangXueliang,LiuXiaofeng,WangYaojun.DepartmentofGastroenterology,Ji’nanMilitaryGeneralHospital,Ji’nan250031,China

    Correspondingauthor,WuYing,E-mail:leaf19832200@sina.com

    Abstract【】Hepatic cirrhosis is a common chronic digestive disease in clinical practice, which is the end-stage progression of a variety of liver diseases. Patients with decompensated cirrhosis tend to present with multiple serious complications and may even die. Stem cells are pluripotent cells and have the potential of self-renewing. In recent years, along with the maturity and development of stem cell technique, favorable clinical efficacy has been achieved in the application of stem cell transplantation in treating liver cirrhosis and it has a promising prospect. In this paper, the current situation and research progress of stem cell transplantation in treating liver cirrhosis were elaborated. ......