【摘要】 类风湿关节炎(RA)是一种累及全身多系统的自身免疫性疾病。RA的共病现象增加了临床诊疗的难度，备受临床医师的广泛关注。近年来，人们对于RA合并冠状动脉粥样硬化性心脏病(CHD)有了突破性认知，炎症和动脉粥样硬化可能存在相似的病理生理通路，RA患者更易出现进展性和较严重的CHD表现。识别RA合并CHD的危险因素对提高预测心血管疾病风险的能力、早期降低全身炎症治疗具有重要的积极作用。

    【关键词】 类风湿关节炎;冠状动脉粥样硬化性心脏病;机制;诊断;治疗

    【Abstract】 Rheumatoid arthritis (RA) is a systemic autoimmune disease. The comorbidity of RA has captivated widespread attention from clinicians， which significantly increases the difficulty of clinical diagnosis and treatment. In recent years， breakthrough has been reached in the understanding of RA complicated with coronary heart disease (CHD). Inflammation and atherosclerosis may share similar pathophysiological pathways ......