林慧?刘肖?梁清妹?蔡柳洪

    【摘要】目的 探讨体质量管理对肥胖型多囊卵巢综合征(PCOS)不孕症女性的内分泌激素水平和辅助生育结局的影响。方法 收集62例进行辅助生殖技术(ART)治疗的肥胖型PCOS不孕症患者的临床资料，选择接受常规辅助生育治疗的28例患者为对照组，在常规辅助生育治疗的基础上接受定期体质量管理的34例患者为体质量管理组。比较2组患者的内分泌激素水平和辅助生育结局。结果 减重后，体质量管理组肥胖型PCOS患者的体质量、BMI、体脂、腰臀均较减重前以及对照组降低(P均 0.05)。结论 体质量管理可以有效降低肥胖型PCOS不孕症患者的BMI、空腹胰岛素水平，可能潜在地改善其辅助生育的妊娠结局。

    【关键词】体质量管理;肥胖;多囊卵巢综合征;性激素;胰岛素;辅助生育

    Effect of weight loss on endocrine hormonal levels and assisted reproductive outcomes of obese PCOS women Lin Hui， Liu Xiao， Liang Qingmei， Cai Liuhong. Reproductive Center， the Third Affiliated Hospital of Sun Yat-sen University， Guangzhou 510630， China Corresponding author， Cai Liuhong， E-mail： 446870080@qq.com

    【Abstract】Objective To investigate the effect of weight loss on the endocrine hormonal levels and assisted reproductive outcomes of women with obese polycystic ovarian syndrome (PCOS). Methods Clinical data of 62 obese women with PCOS receiving assisted reproductive techniques (ART) were collected. All women were divided into the control (n = 28) and weight loss groups (n = 34). In the control group ......