邱韵歌?肖晗?文勇

    【摘要】 上颌窦位于上颌骨内，呈金字塔形，体积为12～15 cm3。由于其特殊的结构和位置，上颌窦底提升术在植入材料、术式选择及并发症处理方面面临不断更新与挑战。浓缩生长因子(CGF)作为第3代血小板浓缩物，具有致密的网格结构，缓慢释放生长因子，使组织愈合过程趋于自然，可有效促进软硬组织再生及创口愈合。近年来，CGF凭借其独有的优势在口腔种植领域占有一席之地，并已广泛应用于上颌窦底提升术。本文就其在上颌窦底骨增量和窦底黏膜修补的相关研究进行综述，以期为CGF的临床应用提供可靠的理论依据。

    【关键词】 浓缩生长因子;上颌窦底提升术;种植;黏膜穿孔;窦底黏膜修补

    Research progress on application of concentrated growth factors in maxillary sinus augmentation and sinus mucosal repair Qiu Yunge， Xiao Han， Wen Yong. Department of Oral Implantology， School and Hospital of Stomatology， Cheeloo College of Medicine， Shandong University， Shandong Key Laboratory of Oral Tissue Regeneration， Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration， Jinan 250012， China

    Corresponding author， Wen Yong， E-mail： wenyong@sdu.edu.cn

    【Abstract】 The maxillary sinus is pyramid-shaped with a volume of 12-15 cm3， located in the maxilla. Due to its special structure and location， maxillary sinus elevation is faced with challenges of bone graft materials， surgical methods and management of complications. Concentrated growth factors (CGF) is the third generation of platelet concentrate with a dense grid structure ......