刘松惠?刘珂珂?付连国?刘志荣

    【摘要】男性感染人乳头瘤病毒(HPV)会严重影响其身体健康，HPV与尖锐湿疣、阴茎癌、肛门癌、口腔和口咽疾病密切相关。已有研究表明，HPV疫苗对男性HPV感染性疾病具有较好的预防效果，尤其是针对特殊人群。然而，男性接种HPV疫苗的认知程度低和HPV疫苗供应短缺，导致男性HPV疫苗接种率不理想。该文对男性HPV感染情况、接种HPV疫苗对男性HPV感染相关疾病的预防效果、男性接种HPV疫苗的可能障碍进行综述，并提出推广男性接种HPV疫苗的建议。笔者认为，应加强HPV疫苗接种相关知识健康教育，提供相关医疗咨询服务和疫苗开发，以提高男性HPV疫苗接种率。

    【关键词】人乳头瘤病毒；疫苗；男性；尖锐湿疣；阴茎癌；肛门癌

    A systematic review of research progress in preventive effect of HPV vaccine in men Liu Songhui△， Liu Keke， Fu Lianguo， Liu Zhirong.△Bengbu Medical College， Bengbu 233000， China

    Corresponding author， Liu Zhirong， E-mail： lzr@androl.cn

    【Abstract】 Human papillomavirus (HPV) infection in men can severely affect male health. HPV is closely associated with condyloma acuminatum， penile cancer， anal cancer， oral cavity and oropharyngeal diseases， etc. Studies have shown that HPV vaccine exerts favorable preventive effect on male infectious diseases， especially for special populations. However， low awareness of HPV vaccination among men and the shortage of HPV vaccine supply have led to unsatisfactory HPV vaccination rates among men. In this article ......