针刺调控哮喘相关第2组先天淋巴样细胞功能的研究进展
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【摘要】 文章综合国内外文献,从第2组先天淋巴样细胞(ILC2)在支气管哮喘(哮喘)发病过程的作用、针刺调控ILC2治疗哮喘的研究两方面进行总结。研究初步表明针刺可能是通过影响ILC2的分泌和迁移功能等途径,达到减轻哮喘气道炎症、抑制气道高反应性、改善气道重塑的目的,但现有仍存在针刺调控哮喘的ILC2相关通路尚未明确、动物实验及临床研究少、缺乏针刺经ILC2s途径改善激素抵抗性哮喘的机制研究等问题。【关键词】 针刺;第2组先天淋巴样细胞;支气管哮喘;糖皮质激素
Research progress on acupuncture regulation of asthma related group 2 innate lymphoid cell function
DONG Min1, LI Hao1, PAN Jiaxin1, ZHANG Kun1,2,3 , GUO Bin4
(1.Department of Acupuncture and Moxibustion, Zhaoqing Hospital, the Third Affiliated Hospital of Sun Yat-sen University, Zhaoqing 526040, China; 2. Department of Acupuncture and Moxibustion, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China; 3. Department of Allergy, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China;
4. Ningxia Medical University, Yinchuan 750004, China)
Corresponding author: ZHANG Kun, E-mail: 1486644904@qq.com
【Abstract】 This paper reviews the role of innate lymphoid cells (ILC2s) in the pathogenesis of bronchial asthma and explores the evidence for acupuncture’s regulatory effects on ILC2s in asthma treatment. Preliminary findings suggest that acupuncture may mitigate airway inflammation ......
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