秦斌 闫研 殷果 庾红萍 王炳志 王铁杰

    摘 要 目的：建立快速测定肉桂药材水分的方法。方法：采用甲苯法测定药材样品含水量(作为参考值)。采用近红外光谱法结合偏最小二乘法建立药材样品水分的定量模型。根据药材样品水分测定参考值，采集80批药材样品，以常数偏移消除法预处理光谱，药材样品水分测定最佳波段范围为7 502.2～6 896.6、5 600.6～4 998.9 cm-1。结果：药材样品水分定量模型的内部交叉验证决定系数(R2)为0.974 9，交叉验证均方差为0.404；模型外部验证R2为0.940 4，预测均方差为0.306。结论：该方法快速准确，简便无污染，可用于肉桂药材水分的快速测定。

    关键词 肉桂；近红外光谱法；水分；定量模型

    中图分类号 R927.1 文献标志码 A 文章编号 1001-0408(2018)14-1949-05

    DOI 10.6039/j.issn.1001-0408.2018.14.18

    ABSTRACT OBJECTIVE： To develop a method for rapid determination of water content in Cinnamomum cassia. METHODS： The moisture of sample was determined by toluene method (as reference value). IFRS-PLS was used to establish quantitative correction model of moisture in sample. According to moisture determination of sample， 80 batches of samples were collected， and constant offset elimination method was used to pretreat spectrum. The optimal spectrum range for moisture determination of medicinal sample were 7 502.2-6 896.6 cm-1 and 5 600.6-4 998.9 cm-1. RESULTS： The internal cross validation decision coefficient (R2) of moisture quantitative correction model was 0.974 9 ......