中图分类号R965；R285 文献标志码A 文章编号 1001-0408(2025)08-1008-05

    DOI 10.6039/j.issn.1001-0408.2025.08.21

    Research progress on the improvement of myocardial fibrosis by traditional Chinese medicine through regulation of NLRP3 inflammasome

    ZHANG Rui'，YAN Jingshun'，JIA Fuyun'，JIA Kexin'，LIU Chenyang'，LIU ，LI ，XU Qiang2(1. Graduate SchoolTianjin University of Traditional Chinese Medicine， Tianjin 3016l7， China；2.Dept.of Cardiology，the Second Afiliated Hospital of Tianjin University of Traditional Chinese Medicine， Tianjin 300150， China)

    ABSTRACTMyocardialfibrosis(MF)，characterizedbydecreased cardiacfunction and myocardial compliance，isa pathologicalprocessandaprogressionfactorinvariouscardiovasculardiseasesThenucleotide-bindingdomainleucine-richrepeat and pyrindomain-containingreceptor 3(NLRP3)inflammasome iscloselyrelated tothedevelopmentof MF.Recent studies have shownthattraditionalChinesemedicine(TCM)canregulatetheNRPinflammasometoaleviateMFBasedonthisthisarticle systematicallysummarizestheresearchprogressonthemechanismsbywhichTCMregulatestheNLRP3inflammasometo improve MF.It is foundthatactiveingredientsof TCM ......