中图分类号R283；R285 文献标志码A 文章编号 1001-0408(2025)13-1587-06

    DOI 10.6039/j.issn.1001-0408.2025.13.06

    Studyon stir-frying processof Platycodon grandiflorumand itsprotective effect onacute lung injury in mice before and after stir-frying

    HAN Xiaotian，WANG Lei， WANG Yaping，YANG Yaling，QI Bin(School of Pharmacy， Changchun University ofChineseMedicine，Changchun130117，China)

    ABSTRACTOBJECTIVETooptimize the stir-fryingprocessof Platycodon grandiflorum，compare the protectiveeffectof P. grandiflorumonlunginjuryinmicebeforeandafterstir-frying，andpreliminarilyexplorethecharacteristicsof“enhancedefcacy through processing”of stir-frying P. grandiflorum. METHODS On the basis of single-factor experiment，the stir-frying time， temperatureandfrequencyweretakenasfactors，andthecomprehensivescoresofappearancetraits，platycodinDcontentand alcohol extractcontentweretakenasindexes.Box-Behnkenresponsesurfaceexperiment was designed tooptimizethestir-frying process of P. grandiflorum and verify it.The mice were divided into blank control group ......