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编号:2390012
指纹图谱结合药效成分含量综合评价银丹活血通瘀颗粒质量
http://www.100md.com 2025年8月18日 中国药房 2025年第14期
内酯,人参,靶点
    

    中图分类号R917 文献标志码A 文章编号 1001-0408(2025)14-1743-06

    DOI 10.6039/j.issn.1001-0408.2025.14.09

    ABSTRACTOBJECTIVEToevaluate thequalityof Yindan huoxue tongyu granules.METHODS Taking high performance liquidchromatographywithultravioletandevaporativelightscateringdetectionasmethod,thefingerprintof15batchesofYindan huoxuetongyugranuleswasestablished,andsimilarityevaluationwasperformedby SimilarityEvaluationSystemof ChromatographicFingerprintofTCM(2012edition)todeterminecommonpeaks.Thecommonpeakswere identified by comparingwithreferencesubstancechromatogramsandsingledecoctionpiecechromatograms.Networkpharmacologywasusedto screenoutcoretargetsandpathwaysof identifiedcomponents,constructa“component-target-pathway”network diagram,and predictthe pharmacodynamiccomponentsof Yindan huoxuetongyu granules,and the content determinationof these components wascarriedoutbythe samemethod.RESULTSHPLC fingerprintsof15 batchesof Yindanhuoxue tongyugranules were characterized with 40 common peaks,and17components including salvianolic acid B ......

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