负载盐酸万古霉素的聚多巴胺纳米粒的制备及其联合光热的抗菌作用研究


中图分类号R917;R943 文献标志码A 文章编号 1001-0408(2025)15-1887-06
DOI10.6039/j.issn.1001-0408.2025.15.12
Preparation of vancomycin hydrochloride-loaded polydopamine nanoparticles and their antimicrobial effect in combination with photothermal therapy
PAN Lihual,2,LIU Bin3 , JIANG Xiayun2,ZHOU Xiaopeng2(1. School of Pharmacy, Zhejiang Chinese Medical University,Hangzhou 310053,China;2.Dept.of Pharmacy,Lishui People’s Hospital,Zhejiang Lishui 323000,China;3.Dept.of Orthopaedics,Lishui Municipal Central Hospital,Zhejiang Lishui 3230o0,China)
ABSTRACTOBJECTIVE To prepare vancomycin hydrochloride(VH)-loaded polydopamine (PDA) nanoparticles (VH@PDA nanoparticles),andstudytheirantimicrobialeffectincombinationwithphotothermaltherapyMETHODSUsingPDAasthe carier,VH was loaded to prepare VH@PDAnanoparticles(PDA nanoparticles were preparedusing thesame method).The nanoparticleswerecharacterizedwithlaserparticlesizeanalyzer ......
您现在查看是摘要页,全文长 16753 字符。