基于谱学技术鉴别4种龙胆科“地格达”类蒙药材(1)
[摘要] 为探讨谱学技术在龙胆科“地格达”类蒙药材鉴别中的应用，分别采用近红外光谱分析和差示扫描量热分析技术对4种龙胆科“地格达”类蒙药材进行研究，并对得到的特征图谱进行系统分析。在近红外一维图谱4 250～4 400，5 650～5 800 cm-1四者存在一定差异，在二阶导数图谱4 100～4 400，4 401～4 900，5 400～5 800 cm-1四者呈现显著差异;并且四者的DSC曲线具有明显不同的拓扑图形、特征峰及峰顶温度。通过近红外光谱分析和差示扫描量热分析2种谱学技术可实现4种龙胆科“地格达”类蒙药材的高效、准确鉴别，为龙胆科“地格达”类蒙药材的快速鉴别提供科学依据。
[关键词] “地格达”类蒙药; 鉴别; 近红外光谱分析; 差示扫描量热分析
[收稿日期] 2014-11-21
[基金项目] 国家自然科学基金项目(81303306，81106504，81060372);国家“十二五”科技支撑计划项目 (2012BAI28B02);内蒙古自治区高等学校“青年科技英才支持计划”项目(NJYT-13-B18);大学生创新创业训练计划项目(201410061159);内蒙古自治区高等学校科学研究项目(NJZY12222);中医药行业专项(201407003)
, 百拇医药
[通信作者] 李旻辉，教授，硕士生导师，E-mail： li_minhui@aliyun.com
[作者简介] 吕丽娟，讲师，E-mail： lv_lijuan@aliyun.com
Study on identification of four kinds of Gentianaceae Mongolian
medicine Digeda with spectroscopy techniques
LV Li-juan， GUO Yong-hui， ZHAO Ya-chan， ZHAO Dong-dong， LI Min-hui
(1. Department of Basic Science， Tianjin Agricultural University， Tianjin 300384， China;
, 百拇医药
2. National Resource Center for Chinese Materia Medica， China Academy of Chinese Medicinal Sciences， Beijing 100700， China;
3. Hebei Institute for Drug Control， Shijiazhuang 050011， China;
4. Baotou Medical College， Baotou 014060， China)
[Abstract] To study the identification of Gentianaceae Mongolian medicine Digeda with spectroscopy techniques， near infrared spectroscopy and differential scanning calorimetry techniques were applied to study on the identification of 4 kinds of Gentianaceae Mongolian medicine Digeda， and characteristic spectrums obtained were systematically analyzed. In NIR study， the four species of Digeda exist some differences in 4 250-4 400 cm-1 and 5 650-5 800 cm-1 of one-dimensional spectra， and show significant differences in 4 100-4 400 cm-1， 4 401-4 900 cm-1 and 5 400-5 800 cm-1 of the second derivative spectra. DSC curves of them present distinct topological pattern， characteristic peak and peak temperature. Using near infrared spectroscopy and differential scanning calorimetry analysis can realize efficient and accurate identification of four kinds of Mongolian medicine Digeda， and provide scientific basis for the efficient and accurate identification of other Gentianaceae Mongolian medicine Digeda.
[Key words] Mongolian medicine Digeda; identification; near infrared spectroscopy; differential scanning calorimetry, 百拇医药(吕丽娟 郭永辉 赵雅婵 赵冬冬 李旻辉)
[关键词] “地格达”类蒙药; 鉴别; 近红外光谱分析; 差示扫描量热分析
[收稿日期] 2014-11-21
[基金项目] 国家自然科学基金项目(81303306，81106504，81060372);国家“十二五”科技支撑计划项目 (2012BAI28B02);内蒙古自治区高等学校“青年科技英才支持计划”项目(NJYT-13-B18);大学生创新创业训练计划项目(201410061159);内蒙古自治区高等学校科学研究项目(NJZY12222);中医药行业专项(201407003)
, 百拇医药
[通信作者] 李旻辉，教授，硕士生导师，E-mail： li_minhui@aliyun.com
[作者简介] 吕丽娟，讲师，E-mail： lv_lijuan@aliyun.com
Study on identification of four kinds of Gentianaceae Mongolian
medicine Digeda with spectroscopy techniques
LV Li-juan， GUO Yong-hui， ZHAO Ya-chan， ZHAO Dong-dong， LI Min-hui
(1. Department of Basic Science， Tianjin Agricultural University， Tianjin 300384， China;
, 百拇医药
2. National Resource Center for Chinese Materia Medica， China Academy of Chinese Medicinal Sciences， Beijing 100700， China;
3. Hebei Institute for Drug Control， Shijiazhuang 050011， China;
4. Baotou Medical College， Baotou 014060， China)
[Abstract] To study the identification of Gentianaceae Mongolian medicine Digeda with spectroscopy techniques， near infrared spectroscopy and differential scanning calorimetry techniques were applied to study on the identification of 4 kinds of Gentianaceae Mongolian medicine Digeda， and characteristic spectrums obtained were systematically analyzed. In NIR study， the four species of Digeda exist some differences in 4 250-4 400 cm-1 and 5 650-5 800 cm-1 of one-dimensional spectra， and show significant differences in 4 100-4 400 cm-1， 4 401-4 900 cm-1 and 5 400-5 800 cm-1 of the second derivative spectra. DSC curves of them present distinct topological pattern， characteristic peak and peak temperature. Using near infrared spectroscopy and differential scanning calorimetry analysis can realize efficient and accurate identification of four kinds of Mongolian medicine Digeda， and provide scientific basis for the efficient and accurate identification of other Gentianaceae Mongolian medicine Digeda.
[Key words] Mongolian medicine Digeda; identification; near infrared spectroscopy; differential scanning calorimetry, 百拇医药(吕丽娟 郭永辉 赵雅婵 赵冬冬 李旻辉)