免疫球蛋白轻链在糖尿病肾病中的表达及意义(1)
【摘 要】目的:探讨免疫球蛋白轻链(FLCs)在糖尿病肾病中的表达。方法:选我院45例糖尿病肾病患者为试验组,同时选45例非糖尿病肾病慢性肾疾病患者为对照组,比较组间FLCs检测结果及差异。结果:试验组患者的κFLC、λFLC和cFLC水平均高于对照组(P<0.05),试验组患者的肾间质小管病变与cFLC也呈正相关,与对照组慢性肾疾病的患者呈负相关。结论:免疫球蛋白轻链(FLCs)水平可以用来作为患者糖尿病肾病的病理学诊断的辅助作用。【关键词】免疫球蛋白轻链;糖尿病肾病;病情诊断;肾损害
【中图分类号】R587.24 【文献识别码】B 【文章编号】1002-8714(2019)11-0024-02
【Abstract】 Objective To investigate the expression of immunoglobulin light chain (FLCs) in diabetic nephropathy. Methods Forty-five patients with diabetic nephropathy were selected as the experimental group. 45 patients with non-diabetic nephropathy and chronic kidney disease were selected as the control group. The results and differences of FLCs between the groups were compared. Results The levels of κFLC ......
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