【摘 要】目的：探讨CYP2C19基因与冠脉病变是否存在相关性。方法：选取2018-2019年于我院冠心病患者50名，采用SYNTAX评分将冠脉严重程度分级，采用基因芯片技术检测CYP2C19基因多形态性，分析CYP2C19的基因多形态性在冠脉病变是否存在关联性。结果：不同代谢型患者冠脉严重程度无统计学意义(P<0.05)。结论：通过CYP2C19基因预测冠脉严重程度尚不确切。

    【关键词】CYP2C19 基因多形态 冠脉严重程度

    【中图分类号】R541.4 【文献标识码】B 【文章编号】1002-8714(2020)09-0106-01

    【Abstract】Objective： To investigate the correlation between CYP2C19 gene and coronary artery disease. Methods： 50 patients with coronary heart disease in our hospital from 2018 to 2019 were selected. The severity of coronary artery was graded by SYNTAX score. CYP2C19 gene polymorphism was detected by gene chip technology ......