经肝动脉化疗栓塞对肝癌术后复发及预后的临床研究
 |
| 第1页 |
参见附件(1833KB，3页)。
【摘要】 目的 探讨经肝动脉化疗栓塞对预防肝癌术后复发和预后的价值。方法 将81例根治性原发性肝癌患者随机分成两个组。对照组54例行单纯肝癌切除术，术后予口服保肝药物及免疫增强药物等治疗；治疗组27例，行单纯肝癌切除术后一个月开始行经肝动脉化疗栓塞(TACE)。比较两组疗效。结果 随访5年，治疗组和对照组第1年、第2年、第5年肿瘤复发率分别为14.8%、14.8%、35.2%和22.2%、35.2%、81.5%；患者生存率分别为85.2%、70.4%、59.3%和94.4%、72.2%、35.2%；无瘤生存率分别为70.4%、48.1%、44.4%和79.6%、61.1%、18.5%。两组第1年、第2年的肿瘤复发率、患者生存率及无瘤生存率比较差异均无统计学意义(P>0.05)，第5年治疗组的肿瘤复发率显著低于对照组(P<0.05)，患者生存率及无瘤生存率均显著高于对照组(P<0.05)。结论 原发性肝癌根治术后辅助TACE治疗能有效提高患者的远期生存率。
【关键词】 原发性肝癌；经肝动脉化疗栓塞术；复发率；生存率
文章编号：1003-1383(2011)04-0403-03 中图分类号：R 735.7 文献标识码：A
doi:10.3969/j.issn.1003-1383.2011.04.001
Clinical research on the recrudesce and prognosis of liver cancer with TACE
WEI Zhonghong,PU Jian,MA Yanfei, WANG jianchu, LU Guanmin, WEI Bangning
(Department of Hepatobiliary Surgery,the Affiliated Hospital of Youjiang Medical University
For Nationalities,Baise,Guangxi 533000,P.R.China)
【Abstract】 Objective To study the recrudesce and prognosis of liver cancer with transcatheter hepatic arterial chemoembolization (TACE).Methods 81 cases of radical cure for primary liver cancer were randomly divided into two groups. The control group (54 cases) were simply treated with hepatic carcinectomy,and thereafter with oral drugs for liver protection and drugs for immunity enhancement, while the observed group(27cases) were treated with TACE one month after hepatic carcinectomy. The efficacies of the treatment of the two groups were compared.Results There was a follow-up study of 5 years for the two groups. The recrudesce rates of cancer in the observed groupand the control group for the 1st, 2nd and 5th year were,respectively,14.8%,14.8%,35.2% and 22.2%,35.2%,81.5%. The survival rates were 85.2%,70.4%,59.3% and 94.4%,72.2%,35.2%,respectively. The tumor-free survival rates were 70.4%,48.1%,44.4% and 79.6%,61.1%,18.5%,respectively.The rates of cancer recrudesce,survival and tumor-free survival in the two groups for the 1st and 2nd year had no significant difference(P>0.05).The rate of cancer recrudesce in the observed group for the 5th year was obviously lower than that in the control group(P<0 ......
您现在查看是摘要介绍页，详见PDF附件(1833KB，3页)。