骨肉瘤发生发展相关信号通路研究进展(5)
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[26] Yu Py,GR HL,Roberts R,et al.Target specificity,in vivo pharmacokinetics,and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma,Ewing’s sarcoma,and rhabdomyosarcoma[J].PLoS One,2017,12(7):e0181885.
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(收稿日期:2019-03-10 修回日期:2019-03-26)
(編辑:梁明佩), http://www.100md.com(卓航宇 唐毓金)
[23] Yu H,Pardoll D,Jove R.STATs in cancer inflammation and immunity:a leading role for STAT3[J].Nat Rev Cancer,2009,9(11):798809.
[23] Darnell JE,Kerr IM,Stark GR.JakSTAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins[J].Science,1994,264(5164):1415.
[25] Tu B,Du L,Fan QM,et al.STAT3 activation by IL6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma[J].Cancer Letters,2012,325(1):8088.
[26] Yu Py,GR HL,Roberts R,et al.Target specificity,in vivo pharmacokinetics,and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma,Ewing’s sarcoma,and rhabdomyosarcoma[J].PLoS One,2017,12(7):e0181885.
[27] Zhang T,Li J,Yin F,et al.Toosendanin demonstrates promising antitumor efficacy in osteosarcoma by targeting STAT3[J].Oncogene,2017,36(47):66276639.
(收稿日期:2019-03-10 修回日期:2019-03-26)
(編辑:梁明佩), http://www.100md.com(卓航宇 唐毓金)