孤儿核受体Nur77/NR4A1调节巨噬细胞炎症反应研究进展(6)
[26]YIN H M,ZHANG S,SUN Y H,et al.MicroRNA34/449 targets IGFBP3 and attenuates airway remodeling by suppressing Nur77mediated autophagy[J].Cell Death Dis,2017,8(8):e2998.
[27]JIANG Y J,ZENG Y,HUANG X,et al.Nur77 attenuates endothelin1 expression via downregulation of NFκB and p38 MAPK in A549 cells and in an ARDS rat model[J].Am J Physiol Lung Cell Mol Physiol,2016,311(6):L1023L1035.
[28]REDDY A T,LAKSHMI S P,BANNO A,et al.Cigarette smoke downregulates Nur77 to exacerbate inflammation in chronic obstructive pulmonary disease (COPD)[J].PLoS One,2020,15(2):e0229256.
[29]QIN H P,GAO F,WANG Y N,et al.Nur77 promotes cigarette smoke ?偉c induced autophagic cell death by increasing the dissociation of Bcl2 from Beclin1[J].Int J Mol Med,2019:44(1)2536.
[30]PALUMBOZERR K,ZERR P,DISTLER A,et al.Orphan nuclear receptor NR4A1 regulates transforming growth factorβ signaling and fibrosis[J].Nat Med,2015,21(2):150158.
[31]KARKI K,WRIGHT G A,MOHANKUMAR K,et al.A bisindolederived NR4A1 antagonist induces PDL1 degradation and enhances antitumor immunity[J].Cancer Res,2020,80(5):10111023.
(收稿日期:2020-05-05修回日期:2020-05-12)
(編辑:梁明佩), 百拇医药(蒋玉洁 罗维贵 廖品琥)
[27]JIANG Y J,ZENG Y,HUANG X,et al.Nur77 attenuates endothelin1 expression via downregulation of NFκB and p38 MAPK in A549 cells and in an ARDS rat model[J].Am J Physiol Lung Cell Mol Physiol,2016,311(6):L1023L1035.
[28]REDDY A T,LAKSHMI S P,BANNO A,et al.Cigarette smoke downregulates Nur77 to exacerbate inflammation in chronic obstructive pulmonary disease (COPD)[J].PLoS One,2020,15(2):e0229256.
[29]QIN H P,GAO F,WANG Y N,et al.Nur77 promotes cigarette smoke ?偉c induced autophagic cell death by increasing the dissociation of Bcl2 from Beclin1[J].Int J Mol Med,2019:44(1)2536.
[30]PALUMBOZERR K,ZERR P,DISTLER A,et al.Orphan nuclear receptor NR4A1 regulates transforming growth factorβ signaling and fibrosis[J].Nat Med,2015,21(2):150158.
[31]KARKI K,WRIGHT G A,MOHANKUMAR K,et al.A bisindolederived NR4A1 antagonist induces PDL1 degradation and enhances antitumor immunity[J].Cancer Res,2020,80(5):10111023.
(收稿日期:2020-05-05修回日期:2020-05-12)
(編辑:梁明佩), 百拇医药(蒋玉洁 罗维贵 廖品琥)