替罗非班桥接阿替普酶静脉溶栓治疗进展性急性缺血性脑卒中的临床

替罗非班桥接阿替普酶静脉溶栓治疗进展性急性缺血性脑卒中的临床疗效

http://www.100md.com 2025年6月25日右江医学 2025年第4期

     中图分类号：R743.3 文献标志码：A DOI ： 10.3969/j .issn.1003-1383.2025.04.007

    Efficacy of tirofiban bridging with alteplase for intravenous thrombolysis in the treatment of progressive acute ischemic stroke

    (1a.Department of Neurology，1b. Department of Otolaryngology，1. The Second Hospital of Sanming

    City，Yong'an366Ooo，Fujian，China；2.Academician and ExpertWorkstation，FujianPolytechnic ofWaterConservancy and Electric Power，Yong'an 366Ooo，Fujian，China)

    【Abstract】ObjectiveToinvestigatethesafetyandefficacyoftirofibanbridging withalteplaseforintravenous thrombolysisinthetreatmentof progressiveacuteischemicstroke(AIS).MethodsAtotalof76patientswith progressiveAISadmitted tothe Departmentof Neurology atthe Second Hospital of Sanming Cityfrom February 2O21toFebruary2O24 were selectedandrandomlydivided into control groupandobservation group，with38cases ineach group.Thecontrol group were given intravenousthrombolysiswithalteplase，whiletheobservationgroupweregiventirofiban bridging therapyafteralteplase thrombolysis.Andthen，theNational Institutes of Health Stroke Scale(NIHSS)scores at14 daysafterthrombolysis ......

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