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编号:2389329
脂联素联合FGF21与高血压患者冠脉钙化积分的相关性研究
http://www.100md.com 2025年8月12日 右江医学 2025年第6期
     中图分类号:R541.4 文献标志码:A DOI : 10.3969/j .issn.1003-1383.2025.06.003

    Study on correlation between adiponectin combined with FGF21 and coronary artery calcification score in hypertensive patients

    LI Kela,CEN Tuan, PAN Zheng (Department of Cardiovascular Medicine,Affliated Hospital of Youjiang Medical Universityfor Nationalities,Baise533Ooo,Guangxi,China)

    【Abstract】ObjectiveToexplore theexpresioncharacteristicsof serumadiponectinandfibroblastgrowth factor 21 (FGF21)inhypertensioncombined with coronaryarterycalcificationandtheircorelation withcalcificationscore bydetecting theexpressionlevelsof thesetwofactorsinhypertensivepatients withcoronaryarterycalcification.Methods46patients with primaryhypertensioncombinedwithcoronaryarterycalcificationwereselectedasexperimentalgroup,and42patientswith hypertension without coronaryartery calcification wereselectedas control group.Fasting blood was drawn todetectserum homocysteine,lipids,uricacid,C-reactive protein,andfasting bloodglucosebyalargebiochemicaldetector,andcoronary artery calcification wasexaminedandscoredbychest CT.The levelsof serumadiponectinandFGF21 were detected by enzym-linked immunosorbentassy(ELISA) ......

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