李岩峰 房祥芳 王忠永

    【摘 要】痤疮是临床上常见的皮肤病之一，临床表现为面部粉刺、丘疹、脓疱，反复发作会遗留色素沉着或瘢痕，严重影响患者的生理、心理和社会交往。目前，临床关于痤疮的发病机制尚未完全明确，普遍认为皮脂腺分泌过度、毛囊皮脂腺导管角化异常、痤疮丙酸杆菌及炎症与免疫因素是主要病机。而饮食与痤疮的关系尚存在争议，因此本文结合现有相关文献，介绍了饮食对胰岛素样生长因子-1、皮脂腺、炎症、皮肤微生物群以及痤疮丙酸杆菌的影响，旨在为痤疮患者的正确、合理饮食和预防提供指导。

    【关键词】痤疮；饮食；痤疮丙酸杆菌；皮肤屏障

    中图分类号：R758.73+3 文献标识码：A 文章编号：1004-4949(2023)02-0147-04

    The Role of Diet in the Pathogenesis of Acne

    LI Yan-feng， FANG Xiang-fang， WANG Zhong-yong

    (Department of Dermatology and Venereal Diseases， Binzhou Medical University Hospital， Binzhou 256600， Shandong， China)

    【Abstract】Acne is one of the common skin diseases in clinic. The clinical manifestations are facial acne， papules and pustules. Repeated episodes will leave pigmentation or scars， which seriously affect the patient’s physiological， psychological and social interaction. At present， the clinical pathogenesis of acne is not completely clear. It is generally believed that excessive secretion of sebaceous glands， abnormal keratinization of hair follicle sebaceous ducts， Propionibacterium acnes， inflammation and immune factors are the main pathogenesis. However ......