郝欣

    【摘 要】目的 觀察麝香保心丸联合硝苯地平控释片治疗高血压合并冠心病的临床效果。方法 选择我院2022年1月-9月收治的122例高血压合并冠心病患者为研究对象，随机分为对比组和试验组，各61例。对比组使用贝那普利片联合硝苯地平控释片，试验组在对比组基础上加用麝香保心丸，比较两组临床疗效、心功能指标、血压控制情况、炎症因子水平、住院时间与冠心病相关临床指标。结果 试验组治疗总有效率高于对比组(P<0.05)；试验组LVEF、6MWD高于对比组，LVDD、LVDS低于对比组(P<0.05)；试验组舒张压、收缩压、收缩压负荷、舒张压负荷均低于对比组(P<0.05)；试验组CRP、IL-6、TNF-α及住院时间均低于对比组(P<0.05)；试验组缺血发作频率、发作持续时间、ST段下移距离、Hcy均低于对比组(P<0.05)。结论 麝香保心丸联合硝苯地平控释片治疗高血压合并冠心病效果较好，可在较为安全的情况下控制血压，改善心功能，值得临床应用。

    【关键词】中西医联合用药；高血压；冠心病

    中图分类号：R544.1； R541.4 文献标识码：A 文章编号：1004-4949(2023)04-0145-04

    Clinical Effect of Shexiang Baoxin Pills Combined with Nifedipine Controlled-release Tablets in the Treatment of Hypertension Complicated with Coronary Heart Disease

    HAO Xin

    (Department of Pharmacy， Beijing Tongzhou District Hospital of Integrative Medicine， Beijing 101100， China)

    【Abstract】Objective To observe the clinical effect of Shexiang Baoxin pills combined with Nifedipine controlled-release tablets in the treatment of hypertension complicated with coronary heart disease. Methods A total of 122 patients with hypertension and coronary heart disease admitted to our hospital from January to September 2022 were randomly divided into control group and experimental group ......