廉琛 李东霞 杨雪滢

    【摘 要】外泌体是一种几乎所有细胞都可分泌的微小囊泡，由细胞经胞吐作用产生，并作用于靶细胞产生效应。外泌体能够传递多种生物信号，参与多种生理、病理过程，还可以作为生物标记物、治疗药物、药物载体、治疗靶点等。因此，外泌体在皮肤科学相关领域中具有重要意义。本文就外泌体及外泌体在皮肤科疾病的相关研究进展作一综述，以期为皮肤科相关疾病的诊断和治疗提供新的策略与可能。

    【关键词】细胞外囊泡；外泌体；炎症性皮肤病；皮肤肿瘤

    中图分类号：R751文献标识码：A文章编号：1004-4949(2023)05-0159-04

    Research Progress of Exosomes in Dermatology

    LIAN Chen， LI Dong-xia， YANG Xue-ying

    (Department of Dermatology， Affiliated Hospital of Inner Mongolia Medical University， Hohhot 010050， Inner Mongolia， China)

    【Abstract】Exosomes are small vesicles secreted by almost all cells， which are produced by cells through exocytosis and act on target cells to produce effects. Exosomes can transmit a variety of biological signals， participate in a variety of physiological and pathological processes， and can also be used as biomarkers， therapeutic drugs， drug carriers， therapeutic targets， etc. Therefore exosomes are also important in related fields of dermatology. This article reviews the research progress of exosomes and exosomes in dermatological diseases， in order to provide new strategies and possibilities for the diagnosis and treatment of dermatological diseases. ......