王化秀

    【摘 要】目的 探究他克莫司软膏联合二氧化碳点阵激光治疗白癜风的临床疗效。方法 选取2021年1月-2022年1月就诊于我院的50例白癜风患者为研究对象，采用随机数字表法分为参考组和观察组，每组25例。参考组采用他克莫司软膏治疗，观察组在参考组的基础上采用二氧化碳点阵激光治疗，比较两组临床疗效、炎性因子水平[肿瘤坏死因子-α(TNF-α)、γ-干扰素(IFN-γ)、白介素-17(IL-17)]及不良反应发生情况。结果 观察组治疗总有效率高于参考组，差异有统计学意义(P0.05)。结论 对白癜风患者采用二氧化碳点阵激光临床效果较好，可降低患者的炎症反应，且不会增加不良反应。

    【关键词】白癜风；二氧化碳点阵激光；皮肤瘙痒

    中图分类号：R758.4+1 文献标识码：A 文章编号：1004-4949(2023)06-0029-04

    Clinical Effect of Carbon Dioxide Lattice Laser Combined with Tacrolimus Ointment in the Treatment of Vitiligo

    WANG Hua-xiu

    (Department of Dermatology， Xintai Peoples Hospital， Xintai 271200， Shandong， China)

    【Abstract】Objective To explore the clinical efficacy of tacrolimus ointment combined with carbon dioxide lattice laser in the treatment of vitiligo. Methods A total of 50 patients with vitiligo who were admitted to our hospital from January 2021 to January 2022 were selected as the research objects. They were divided into reference group and observation group by random number table method ......