潘霞

    【摘 要】目的 分析5-氨基酮戊酸光动力疗法(ALA-PDT)联合干扰素针在女性尖锐湿疣治疗中的应用效果。方法 选取2021年5月-2022年9月我院收治的74例女性尖锐湿疣患者，随机分为对照组与观察组，各37例。对照组采取CO2激光治疗，观察组实施ALA-PDT联合干扰素针治疗，比较两组临床疗效、HPV6/11型DNA载体数量、炎性因子水平、免疫功能指标。结果 观察组治疗总有效率为94.59%，高于对照组的78.38%，差异有统计学意义(P<0.05)；观察组治疗后HPV6/11型DNA载量、白介素-2(IL-2)、肿瘤坏死因子-α(TNF-α)、白介素-8(IL-8)均优于对照组，差异有统计学意义(P<0.05)；观察组治疗后CD4+、CD8+及CD4+/CD8+均优于对照组，差异有统计学意义(P<0.05)。结论 LAL-PDT联合干扰素针有助于改善女性尖锐湿疣患者免疫功能及炎性反应，提高治疗效果。

    【关键词】尖锐湿疣；干扰素针；5-氨基酮戊酸光动力疗法

    中图分类号：R752.5+3 文献标识码：A 文章编号：1004-4949(2023)08-0141-04

    Clinical Value of 5-aminolevulinic Acid Photodynamic Therapy (ALA-PDT) Combined with Interferon for Injection in the Treatment of Female Condyloma Acuminatum

    PAN Xia

    (Department of Dermatology， Tai’an Institute of Dermatology， Tai’an 271000， Shandong， China)

    【Abstract】Objective To analyze the application effect of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with interferon for injection in the treatment of female condyloma acuminatum. Methods A total of 74 female patients with condyloma acuminatum admitted to our hospital from May 2021 to September 2022 were randomly divided into control group and observation group ......