袁君

    【摘 要】目的 探讨替硝唑、甲硝唑联合盐酸米诺环素软膏在牙周炎中的应用效果。方法 选择西安碑林和荣口腔诊所2020年5月-2023年2月收治的100例牙周炎患者为研究对象，随机分为研究组和对照组，每组50例。对照组给予盐酸米诺环素软膏治疗，研究组在对照组基础上联合替硝唑、甲硝唑治疗，连续治疗4周后比较两组临床疗效、牙周指标改善情况、炎性因子水平及不良反应发生情况。结果 研究组治疗总有效率为96.00%，高于对照组的78.00%(P0.05)。结论 替硝唑、甲硝唑联合盐酸米诺环素软膏可有效改善牙周功能，抑制炎性反应，临床疗效和安全性较高，对促进牙周炎患者病情康复具有积极意义。

    【关键词】牙周炎；替硝唑；甲硝唑；盐酸米诺环素软膏

    中图分类号：R781.4+2 文献标识码：A 文章编号：1004-4949(2023)17-0122-04

    Application Effect of Tinidazole， Metronidazole Combined with Minocycline Hydrochloride Ointment in Periodontitis

    YUAN Jun

    (Periodontal Department of Beilin Herong Dental Clinic， Xian 710001， Shaanxi， China)

    【Abstract】Objective To investigate the application effect of tinidazole， metronidazole combined with minocycline hydrochloride ointment in periodontitis. Methods A total of 100 patients with periodontitis admitted to Xian Beilin Rongkou Dental Clinic from May 2020 to February 2023 were randomly divided into study group and control group， with 50 patients in each group. The control group was treated with minocycline hydrochloride ointment ......