冯晓阳

    【摘 要】反常性痤疮是一种慢性复发性炎症性皮肤病，临床症状主要表现为患者的腋窝、臀部等部位出现炎症，病因比较复杂且病程较长，易反复发作，严重损害患者的身体健康，降低患者的生活质量。反常性痤疮的确切发病机制尚不清楚，容易与心脑血管疾病并发，还可与其他代谢性疾病一并对患者的健康产生损害，危及患者的生命安全，缩短患者的寿命。虽然反常性痤疮的治疗方式较多，但却很难取得显著效果，反常性痤疮患者的体内出现多种促炎细胞因子水平升高的现象，针对这一症状采取生物制剂治疗成为反常性痤疮治疗的新方式。本文介绍了反常性痤疮的发病机制，并对反常性痤疮的生物制剂治疗进展进行综述，旨在为临床治疗提供依据和参考。

    【关键词】反常性痤疮；生物制剂；生物治疗

    中图分类号：R758.73+3 文献标识码：A 文章编号：1004-4949(2023)17-0186-04

    Research Progress on Biotherapy for Acne Inversa

    FENG Xiao-yang

    (Beijing Health Information Management Teaching and Research Office of Beijing Health Vocational College， Beijing 102433， China)

    【Abstract】Acne inversa is a chronic recurrent inflammatory skin disease， the clinical symptoms are mainly manifested as inflammation in the armpit， hip and other parts. The etiology of the disease is complex and the course of the disease is long， and it is easy to recur， which seriously damages the health of patients and reduces the quality of life of patients. Meanwhile， the exact pathogenesis of acne inversa is not clear， it is easy to be complicated with cardiovascular and cerebrovascular diseases ......