【摘 要】目的 探究异维A酸用于治疗中度寻常痤疮的临床效果。方法 选取渭南市临渭区中医医院2019年8月-2020年8月收治的80例中度寻常痤疮患者为研究对象，根据患者所用治疗方案的不同分为参照组和观察组，每组40例。参照组采用他扎罗汀乳膏进行治疗，观察组采用异维A酸红霉素凝胶进行治疗，比较两组治疗后的皮损情况、临床疗效及不良反应发生情况。结果 观察组治疗后皮损情况优于参照组(P<0.05)；观察组临床治疗总有效率为97.50%，高于参照组的80.00%(P<0.05)；观察组不良反应发生率为0，低于参照组的12.50%(P<0.05)。结论 异维A酸能够改善患者皮损情况，提高临床治疗总有效率，减少不良反应的发生。

    【关键词】异维A酸；中度寻常痤疮；他扎罗汀乳膏

    中图分类号：R758.73+3 文献标识码：A 文章编号：1004-4949(2023)21-0038-03

    Therapeutic Effect of Isotretinoin on Moderate Acne Vulgaris

    ZHU Xiao-jie

    (Pharmacy Department of Linwei District Hospital of Traditional Chinese Medicine， Weinan 714000， Shaanxi， China)

    【Abstract】Objective To explore the clinical effect of isotretinoin in the treatment of moderate acne vulgaris. Methods A total of 80 patients with moderate acne vulgaris admitted to Linwei District Hospital of Traditional Chinese Medicine of Weinan City from August 2019 to August 2020 were selected as the research objects. According to the different treatment schemes used by the patients， they were divided into reference group and observation group ......