【摘 要】目的 探究A型肉毒毒素与得宝松联合治疗甲状腺术后瘢痕的有效性及安全性。方法 选择2020年5月-2021年5月南京医科大学附属常州第二人医院整形美容科收治的60例甲状腺术后瘢痕患者为研究对象，随机分为对照组和观察组，每组30例。对照组采用得宝松注射治疗，观察组采用A型肉毒毒素联合得宝松注射治疗，比较两组临床治疗情况、瘢痕情况和不良反应发生情况。结果 观察组瘢痕颜色、宽度及凸度等临床情况优于对照组；观察组温哥华量表评分、瘢痕宽度、瘢痕评估量表(PSAS)评分及患者满意度评分均优于对照组(P<0.05)；观察组不良反应发生率为3.33%，低于对照组的20.00%(P<0.05)。结论 A型肉毒毒素联合得宝松比单用得宝松治疗甲状腺术后瘢痕效果更加理想，安全性较高，患者满意度高，值得临床应用。

    【关键词】A型肉毒毒素；得宝松；甲状腺；术后瘢痕

    中图分类号：R619+.6 文献标识码：A 文章编号：1004-4949(2023)22-0121-04

    Efficacy of Type A Botulinum Toxin Combined with Diprospan in the Treatment of Scar After Thyroid Surgery

    WU Qi， ZHOU Shan-yu， CAI Yuan-yuan， XIA Yuan， LI Xin-qing

    (Plastic Surgery and Beauty Department of Changzhou Second People’s Hospital Affiliated to Nanjing Medical University， Changzhou 213000， Jiangsu， China)

    【Abstract】Objective To explore the efficacy and safety of type A botulinum toxin combined with diprospan in the treatment of scar after thyroid surgery. Methods From May 2020 to May 2021， 60 patients with scar after thyroid surgery admitted to the Department of Plastic Surgery and Beauty， Changzhou Second People’s Hospital Affiliated to Nanjing Medical University were randomly divided into control group and observation group ......