黄艳

    [摘 要]目的 探讨果酸换肤联合强脉冲光治疗黄褐斑的效果及对皮损评分的影响。方法 选取广州医疗美容诊所有限公司2022年3月-2023年3月收治的76例黄褐斑患者为研究对象，随机分为参照组与治疗组，各38例。参照组给予强脉冲光，治疗组在此基础上给予果酸换肤干预，比较两组治疗效果、氧化应激指标、VISIA皮肤特征及皮损情况。结果 治疗组治疗总有效率为97.37%，高于参照组的84.21%(P<0.05)；治疗组MDA、SOD及GSP-Px指标改善情况优于参照组(P<0.05)；治疗组色素斑、皱纹、纹理、毛孔评分低于参照组(P<0.05)；治疗组皮损评分、经表皮水分流失量低于参照组，皮肤角质层含水量高于参照组(P<0.05)。结论 临床应用果酸换肤联合强脉冲光治疗黄褐斑的疗效确切，可改善皮损程度及氧化应激指标，提高皮肤屏障功能。

    [关键词] 果酸换肤；强脉冲光；黄褐斑；皮损评分

    [中图分类号] R758.42 [文献标识码] A [文章编号] 1004-4949(2024)01-0078-04

    Effect of Glycolic Acid Peels Combined with Intensive Pulsed Light in the Treatment of Chloasma and its Effect on Skin Lesion Score

    HUANG Yan

    (Guangzhou Medical Beauty Clinic Co.， Ltd.， Guangzhou 510010， Guangdong， China)

    [Abstract]Objective To explore the effect ofglycolic acid peels combined with intensive pulsed light in the treatment of chloasma and its effect on skin lesion score. Methods Seventy-six patients with chloasma admitted to Guangzhou Medical Beauty Clinic Co.， Ltd. from March 2022 to March 2023 were selected as study subjects， and were randomly divided into the reference group and treatment group ......