方兴

    [摘 要]目的 探究對激素抵抗特应性皮炎/湿疹患者应用莫匹罗星联合糖皮质激素治疗的效果。方法 选取常州市皮肤病专科医院2020年8月-2021年4月收治的65例激素抵抗特应性皮炎/湿疹患者为研究对象，随机分为对照组(n=32)和研究组(n=33)。对照组予以单一糖皮质激素治疗，研究组予以莫匹罗星联合糖皮质激素治疗，比较两组止痒所需时间、皮损消退时间、临床疗效及并发症发生情况。结果 研究组止痒时间、皮损消退时间均短于对照组，差异有统计学意义(P0.05)。结论 对激素抵抗特应性皮炎/湿疹患者应用莫匹罗星联合糖皮质激素治疗的效果良好，可有效改善患者的临床症状，加速皮肤破损消退和止痒，有利于提升患者的躯体舒适度，加快康复进程，且不良反应发生几率较低，治疗安全性较高。

    [关键词] 激素抵抗特应性皮炎；湿疹；细菌感染；莫匹罗星；糖皮质激素

    [中图分类号] R758.2 [文献标识码] A [文章编号] 1004-4949(2024)03-0059-04

    Clinical Effect of Mupirocin Combined with Glucocorticoid in the Treatment of Steroid-resistant Atopic Dermatitis/Eczema

    FANG Xing

    (Changzhou Dermatology Hospital， Changzhou 213003， Jiangsu， China)

    [Abstract]Objective To explore the effect of mupirocin combined with glucocorticoid in the treatment of patients with steroid-resistant atopic dermatitis/eczema. Methods A total of 65 patients with steroid-resistant atopic dermatitis/eczema admitted to Changzhou Dermatology Hospital from August 2020 to April 2021 were randomly divided into control group(n=32) and study group (n=33). The control group was treated with single glucocorticoid ......