[摘 要]目的 探究超分子水杨酸联合强脉冲光疗法在黄褐斑治疗中的应用价值。方法 选取2022年9月-2023年9月北京绽放研塑医疗美容诊所收治的80例黄褐斑患者为研究对象，分为对照组和观察组，各40例。对照组行强脉冲光疗法治疗，观察组在对照组基础上联合超分子水杨酸治疗，比较两组临床疗效、皮肤图像评分及生理参数。结果 观察组皮损颜色评分、皮损面积评分及MASI评分均低于对照组(P<0.05)；观察组毛孔、色斑、纹理及色素沉着评分均低于对照组(P<0.05)；观察组面颊经皮水分丢失程度低于对照组，表面油脂含量及角质层含水量高于对照组(P<0.05)。结论 强脉冲光疗法联合超分子水杨酸治疗黄褐斑效果较好，不仅能够改善患者的临床症状，还能提升患者的皮肤状态，进而提高整体美观度。

    [关键词] 超分子水杨酸；强脉冲光疗法；黄褐斑

    [中图分类号] R758.4+2 [文献标识码] A [文章编号] 1004-4949(2024)04-0024-04

    Clinical Effect of Supramolecular Salicylic Acid Combined with Intensive Pulsed Light Therapy on Patients with Chloasma

    ZHAO Hai-yue1， TIAN Yan-li2

    (1.Dermatology Department of Beijing Blooming Research Plastic Medical Cosmetic Clinic， Beijing 100010， China； 2.Dermatology Department of ADD+ Medical Esthetic Clinic， Beijing 100020， China)

    [Abstract]Objective To explore the application value of supramolecular salicylic acid combined with intensive pulsed light therapy in the treatment of patients with chloasma. Methods From September 2022 to September 2023，80 patients with chloasma admitted to Beijing Blooming Research Plastic Medical Cosmetic Clinic were selected as the research objects ......