[摘 要]目的 探讨VSD技术联用表皮生长因子对深度烧伤创面愈合及炎症应激反应的影响。方法 选取2022年11月-2023年11月我院收治的深度烧伤患者62例，随机分为对照组和观察组，各31例。对照组应用VSD技术与生理盐水冲洗治疗，观察组在对照组基础上应用表皮生长因子治疗，比较两组创面愈合情况和炎症应激反应情况。结果 观察组创面愈合时间短于对照组，瘢痕生成数及感染数低于对照组(P<0.05)；观察组IL-1、TNF-α、E、NE、R水平低于对照组(P<0.05)。结论 VSD技术结合表皮生长因子能促进深度烧伤患者的创面愈合，提高创面愈合效果，减轻患者炎症应激反应。

    [关键词] VSD技术；表皮生长因子；深度烧伤；创面愈合；炎症应激反应

    [中图分类号] R622 [文献标识码] A [文章编号] 1004-4949(2024)04-0056-03

    Effect of VSD Combined with Epidermal Growth Factor on Wound Healing and Inflammatory Stress Response in Deep Burn

    XU Lu， LUO Jun-jun

    (Department of Laboratory， Xi’an Aerospace General Hospital， Xi’an 710100， Shaanxi， China)

    [Abstract]Objective To investigate the effect of VSD combined with epidermal growth factor on wound healing and inflammatory stress response in deep burn. Methods A total of 62 patients with deep burn admitted to our hospital from November 2022 to November 2023 were randomly divided into control group and observation group ......