[摘 要]目的 探究在老年慢性湿疹患者中应用复方甘草酸苷联合氮卓斯汀治疗的效果及对皮肤美观度的影响。方法 选择2023年2月-6月我院收治的60例老年慢性湿疹患者为研究对象，按照治疗方式不同分为对照组和观察组，每组30例。两组均给予基础干预措施，对照组给予氮卓斯汀治疗，观察组复方甘草酸苷联合氮卓斯汀治疗，比较两组临床疗效、斑疹、结节、风团、水疱、抓痕数量、瘙痒程度、皮肤美观度及不良反应发生情况。结果 观察组治疗总有效率为96.67%，高于对照组的73.33%(P<0.05)；观察组瘙痒、斑疹、结节、风团、水疱、抓痕数量均小于对照组(P<0.05)；两组治疗后FIIQ评分、VSS评分均低于治疗前，且观察组低于对照组(P<0.05)；观察组不良反应发生率为8.00%，低于对照组的24.00%(P<0.05)。结论 复方甘草酸苷联合氮卓斯汀治疗老年慢性湿疹的效果良好，可有效降低皮肤斑疹、结节、风团、水疱、抓痕数量，减轻瘙痒症状，有利于提高皮肤美观度，降低并发症发生几率，值得临床应用。

    [关键词] 复方甘草酸苷；氮卓斯汀；老年慢性湿疹；瘙痒

    [中图分类号] R758.23 [文献标识码] A [文章编号] 1004-4949(2024)04-0063-04

    Effect of Compound Glycyrrhizin Combined with Azelastine in the Treatment of Chronic Eczema in the Elderly and its Effect on Skin Aesthetics

    ZHOU Hong-lei

    (Outpatient Clinic of the Second Retired Cadre Rest Center， Shandong Military Region， Qingdao 266071， Shandong， China)

    [Abstract]Objective To explore the effect of compound glycyrrhizin combined with azelastine on skin aesthetics in elderly patients with chronic eczema. Methods A total of 60 elderly patients with chronic eczema admitted to our hospital from February to June 2023 were selected as the research objects. They were divided into control group and observation group according to different treatment methods ......