[摘 要]目的 研究对痤疮后面部凹陷性瘢痕患者应用重组牛碱性成纤维细胞生长因子凝胶联合CO2点阵激光治疗的效果。方法 选取2019年3月-2022年3月江南大学附属无锡五院/无锡市第五人民医院收治的痤疮后面部凹陷性瘢痕患者80例作为研究对象，按照随机数字表法分为参照组和分析组，每组40例。参照组应用CO2点阵激光治疗，分析组应用重组牛碱性成纤维细胞生长因子凝胶联合CO2点阵激光治疗，比较两组临床疗效、临床指标(结痂时间、疼痛时间、红斑持续时间)、不良反应发生情况。结果 分析组治疗总有效率为95.00%，高于参照组的72.50%(P<0.05)；分析组结痂时间、疼痛时间、红斑持续时间短于参照组(P<0.05)；分析组不良反应发生率为2.50%，低于参照组的22.50%(P<0.05)。结论 重组牛碱性成纤维细胞生长因子凝胶联合CO2点阵激光治疗痤疮后面部凹陷性瘢痕的效果良好，可缩短患者的结痂时间、疼痛时间及红斑持续时间，且安全性较高。

    [关键词]重组牛碱性成纤维细胞生长因子；痤疮；面部凹陷性瘢痕；点阵激光；结痂时间

    [中图分类号] R751 [文献标识码] A [文章编号] 1004-4949(2024)04-0105-04

    Effect of Recombinant Bovine Basic Fibroblast Growth Factor Gel Combined with CO2 Fractional Laser in the Treatment of Facial Depressed Scar After Acne

    YUAN Bo

    (Department of Dermatology， Wuxi Fifth Hospital Affiliated to Jiangnan University/Wuxi Fifth People’s Hospital， Wuxi 214000， Jiangsu， China)

    [Abstract]Objective To study the therapeutic effect of recombinant bovine basic fibroblast growth factor gel combined with CO2 fractional laser on patients with facial depression scar after acne. Methods A total of 80 patients with facial depressed scar after acne admitted to Wuxi Fifth Hospital Affiliated to Jiangnan University/Wuxi Fifth People’s Hospital from March 2019 to March 2022 were selected as the research objects. According to the random number table method ......