[摘 要] 痤疮属于一种因毛囊皮脂腺单位病变所致的皮肤疾病，青少年为高发群体，主要临床表现为炎症病变、结节、丘疹、脓包等，面部、背部、胸部等为其主要发病区域。现阶段，临床尚未具体明确青少年痤疮的发病机制，认为雄激素亢奋、痤疮丙酸杆菌(P.acnes)定植、皮脂分泌异常、炎症反应等因素均可能诱发该病。痤疮的治疗方案多样，包括药膏、口服药物、物理疗法等，但疗效不一。随着医疗技术不断发展，在青少年群体痤疮发病机制、治疗方法等方面研究均取得长足进展。本文就青少年痤疮的发病机制及治疗方法展开综述。

    [关键词] 青少年痤疮；发病机制；雄激素亢奋；炎症反应；物理疗法

    [中图分类号] R758.73+3 [文献标识码] A [文章编号] 1004-4949(2024)04-0192-04

    Research Progress on Pathogenesis and Treatment of Acne

    WANG Chen-jun

    (Department of Dermatology and Venereology， Shannan People’s Hospital， Shannan 856000， Tibet， China)

    [Abstract] Acne is a kind of skin disease caused by the lesions of hair follicle sebaceous gland units， and teenagers are the high incidence group. The main clinical manifestations are inflammatory lesions， nodules， papules， pustules， etc.， and the face， back and chest are the main areas of onset. At present， the pathogenesis of adolescent acne has not been specifically defined in clinic. It is generally believed that hyperandrogen， colonization of propionibacterium acnes (P.acnes)， abnormal sebum secretion， inflammation and other factors may induce the disease. Treatment options for acne are varied ......