蒋桔青

    [摘 要]目的 探析308 nm準分子光联合点阵CO2激光在难治性白癜风中的效果。方法 选取我院2022年4月-2023年9月收治的难治性白癜风患者78例，采用随机抽样法分为参照组和结合组，各39例。参照组应用308 nm准分子光治疗，结合组应用308 nm准分子光联合点阵CO2激光治疗。比较两组白斑面积、血清抗酪氨酸酶抗体水平、氧化应激指标、临床疗效及不良反应发生率。结果 结合组治疗后白斑面积小于参照组(P0.05)。结论 308 nm准分子光联合点阵CO2激光可缩小难治性白癜风患者白斑面积，降低其血清抗酪氨酸酶抗体水平，改善氧化应激指标，且治疗安全性较高。

    [关键词] 308 nm准分子光；点阵CO2激光；难治性白癜风；氧化应激指标

    [中图分类号] R758.4+1 [文献标识码] A [文章编号] 1004-4949(2024)06-0068-04

    Effect of 308 nm Excimer Laser Combined with CO2 Fractional Laser in the Treatment of Refractory Vitiligo

    JIANG Ju-qing

    (Department of Dermatology， Xiangtan Central Hospital， Xiangtan 411100， Hunan， China)

    [Abstract]Objective To explore the effect of 308 nm excimer light combined with CO2 fractional laser in the treatment of refractory vitiligo. Methods A total of 78 patients with refractory vitiligo admitted to our hospital from April 2022 to September 2023 were selected and divided into reference group and combination group by random sampling method ......