[摘 要]目的 探究海藻酸钠修护敷料联合他克莫司软膏辅助治疗儿童特应性皮炎的应用效果。方法 选择2022年1月-12月于我院就诊的儿童特应性皮炎患者64例，随机分为对照组和观察组，各32例。对照组采用他克莫司软膏治疗，观察组在此基础上加用海藻酸钠修护敷料治疗，比较两组临床疗效、不良反应发生情况、生活质量、睡眠质量、皮损面积、疼痛评分及皮肤屏障相关指标。结果 观察组治疗总有效率为93.75%，高于对照组的84.38%(P<0.05)；观察组不良反应发生率为9.38%，低于对照组的18.75%(P<0.05)；观察组生活质量评分为(85.47±8.62)分，高于对照组的(74.62±6.14)分(P<0.05)；观察组皮损面积为(18.74±2.61)mm2，低于对照组的(25.47±3.58)mm2(P<0.05)；观察组疼痛评分为(2.74±0.28)分，低于对照组的(4.52±0.56)分(P<0.05)；观察组治疗后角质层含水量及皮脂含量均高于对照组(P<0.05)。结论 儿童特应性皮炎患者应用海藻酸钠修护敷料联合他克莫司软膏治疗，能够提高临床疗效，改善生活质量、睡眠质量，缩小皮损面积，减轻疼痛感，修复皮肤屏障，减少不良反应发生情况，值得临床应用。

    [关键词] 他克莫司软膏；海藻酸钠修护敷料；儿童特应性皮炎

    [中图分类号] R758.2 [文献标识码] A [文章编号] 1004-4949(2024)11-0108-04

    Application Value of Sodium Alginate Repair Dressing Combined with Tacrolimus Ointment in Adjuvant Treatment of Atopic Dermatitis in Children

    HE Ming-hui

    (Affiliated Hospital of Ya’an Vocational and Technical College， Ya’an 625000， Sichuan， China)

    [Abstract]Objective To explore the application effect of sodium alginate repair dressing combined with tacrolimus ointment in the adjuvant treatment of atopic dermatitis in children. Methods A total of 64 children with atopic dermatitis who were treated in our hospital from January to December 2022 were randomly divided into control group and observation group ......