[摘 要]目的 探究逍遥散加减联合氨甲环酸局部导入在肝郁气滞型黄褐斑患者中的应用价值。方法 选取2021年1月-2024年1月于我院接受治疗的肝郁气滞型黄褐斑患者82例，将其随机分为对照组(n=41)和观察组(n=41)。对照组应用氨甲环酸局部导入治疗，观察组应用逍遥散加减联合氨甲环酸局部导入治疗，比较两组临床疗效、色斑状况、性激素水平。结果 观察组治疗总有效率为95.12%，高于对照组的78.05%(P<0.05)；两组治疗后色斑面积、皮肤颜色评分均降低，且观察组低于对照组(P<0.05)；两组治疗后黄体生成素、卵泡刺激素、雌二醇水平均降低，且观察组低于对照组(P<0.05)。结论 肝郁气滞型黄褐斑患者采用逍遥散加减联合氨甲环酸局部导入治疗，能够提升临床疗效，促进面部色斑状况缓解，改善患者性激素水平，值得应用。

    [关键词] 肝郁气滞型；黄褐斑；逍遥散；氨甲环酸

    [中图分类号] R275.9 [文献标识码] A [文章编号] 1004-4949(2024)12-0048-04

    Effect of Modified Xiaoyao Powder Combined with Local Introduction of Tranexamic Acid in the Treatment of Chloasma of Liver Depression and Qi Stagnation Type

    TU Jing-chen， GUO Wei

    (Pharmacy Department of Xi’an Sanqiao Jingcheng Hospital， Xi’an 710086， Shaanxi， China)

    [Abstract]Objective To explore the application value of modified Xiaoyao powder combined with local introduction of tranexamic acid in patients with chloasma of liver depression and qi stagnation. Methods A total of 82 patients with chloasma of liver depression and qi stagnation type who were treated in our hospital from January 2021 to January 2024 were randomly divided into control group (n=41) and observation group (n=41). The control group was treated with local introduction of tranexamic acid ......