[摘 要]目的 探讨光子嫩肤联合氨甲环酸凝胶贴在中青年黄褐斑女性患者中的应用价值。方法 选择2023年2月-12月平邑县中医医院收治的130例中青年黄褐斑患者作为研究对象，随机分为光子组和凝胶组，各65例。光子组实施光子嫩肤治疗，凝胶组实施光子嫩肤联合氨甲环酸凝胶贴治疗，比较两组MASI评分、皮肤生理参数及不良反应发生率。结果 凝胶组治疗后MASI评分为(5.84±1.19)分，低于光子组的(7.66±1.56)分(P<0.05)；凝胶组治疗后表皮油脂含量为(96.84±12.81)μg/cm2，高于光子组的(91.52±13.35)μg/cm2(P<0.05)；两组经皮水分丢失量、角质层含水量比较，差异无统计学意义(P>0.05)；两组不良反应发生率比较，差异无统计学意义(P>0.05)。结论 光子嫩肤联合氨甲环酸凝胶贴对于中青年黄褐斑患者疗效确切，可促进皮肤屏障修复，优化各项皮肤生理参数，缩小面部黄褐斑面积，且安全性较好，值得应用。

    [关键词] 光子嫩肤；氨甲环酸凝胶贴；黄褐斑

    [中图分类号] R758.42 [文献标识码] A [文章编号] 1004-4949(2024)13-0046-04

    Effect of Photorejuvenation Combined with Tranexamic Acid Gel Patch in the Treatment of Young and Middle-aged Chloasma Patients

    CHEN Ke-li1， XU Shu-jun2

    (1.Suzhou Industrial Park Baodi Technology Co.， LTD.， Suzhou 215128， Jiangsu， China； 2.Pingyi County Hospital of Traditional Chinese Medicine， Linyi 273300， Shandong， China)

    [Abstract]Objective To explore the application value of photorejuvenation combined with tranexamic acid gel patch in young and middle-aged female patients with chloasma. Methods A total of 130 young and middle-aged patients with chloasma admitted to Pingyi County Hospital of Traditional Chinese Medicine from February to December 2023 were randomly divided into photon group and gel group ......